AI-designed viruses mark step toward AI-generated life

2025-09-21 19:36:00 英文原文

作者:— Claire Cameron

Scientists used AI to design viruses for the first time, creating bacteriophages capable of hunting down and killing harmful bacteria.

In the study, which has not yet been peer-reviewed, the researchers describe how they used AI models designed to analyze and generate DNA, RNA, and protein sequences to generate viral genomes with the ability to infect and kill specific strains of Escherichia coli, including some resistant to antibiotics.

Of 302 AI-designed bacteriophages, 16 could infect the bacteria, according to the paper.

The results suggest AI could help design new therapies for treating bacterial infections, but they also offer another tantalizing possibility, one of the researchers told Nature: “The next step is AI-generated life.”

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摘要

Scientists utilized AI to create bacteriophages capable of targeting and eliminating harmful bacteria. In an unpublished study, researchers employed AI models to design viral genomes that can infect and kill specific strains of antibiotic-resistant Escherichia coli. Out of 302 AI-designed phages, 16 were successful in infecting the target bacteria. This research indicates potential for developing new treatments against bacterial infections and hints at future possibilities like creating life with AI.

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